[Lys5,MeLeu9,Nle10]-NKA(4-10) ( —— )

产品货号. M22354 CAS No. 137565-28-7

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

拼团产品询价大包装询价加入购物车

产品名称

[Lys5,MeLeu9,Nle10]-NKA(4-10)
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
产品描述

Highy selective and potent NK2 receptor agonist (IC50 = 6.1 nM). Induces contraction of the rat fundus and bladder (EC50 values are 117 and 10 nM respectively).
同义词

——
通路

GPCR/G Protein
靶点

Neurokinin Receptor
受体

NK2
研究领域

——
适应症

——

CAS Number

137565-28-7
分子量

804
分子式

C39H65N9O9
纯度

>98% (HPLC)
溶解度

water:1 mg/mL
SMILES

CCCC[C@H](NC(=O)[C@H](CC(C)C)N(C)C(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(N)=O
化学全称

——

1. Chassaing et al (1991) Selective agonists of NK-2 binding sites highly active on rat portal vein (NK-3 bioassay). Neuropeptides 19 91 PMID:

计算器

产品手册

关联产品

Neurokinin A(4-10)(T...

Neurokinin A(4-10)(TFA) is an agonist of tachykinin NK2 receptor .
Aprepitant

A potent, orally active, long-acting human NK-1 receptor (substance P receptor) antagonist with IC50 of 0.09 nM.
Substance P (1-9)

Substance P (1-9) is nonapeptide, which decreases the inactivation of substance P by the guinea-pig ileum and urinary bladder. Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons.